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一种用于研究卡波西肉瘤细胞转化的体外模型
JoVE Journal
Biology
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JoVE Journal Biology
An In Vitro Model for Studying Cellular Transformation by Kaposi Sarcoma Herpesvirus
DOI:

09:53 min

August 25, 2017

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Chapters

  • 00:05Title
  • 01:09KSHV Stock Preparation
  • 03:15Transduction of Endothelial Cells with E6 and E7 Papillomavirus Genes
  • 05:41Infection of Transduced Endothelial Cells with KSHV
  • 07:38Results: Phenotypic Changes in KSHV-infected Endothelial Cells
  • 09:15Conclusion

Summary

Automatic Translation

卡波西肉瘤 (KS) 是一种由感染致癌病毒的人 herpesvirus-8/KS 疱疹 (HHV-8/KSHV) 引起的肿瘤。这里描述的内皮细胞培养模型是唯一适合研究 KSHV 转化宿主细胞的机制。

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