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En jämförande studie av drug delivery-metoder riktade till musen innerörat: Bullostomy<em> Versus</em> Transtympanic Injektion
JoVE Journal
Biology
This content is Free Access.
JoVE Journal Biology
A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection
DOI:

09:18 min

March 08, 2017

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Chapters

  • 00:05Title
  • 01:02Auditory Brainstem (ABR) Procedure
  • 03:20Bullostomy
  • 05:57Transtympanic Injection
  • 07:18Results: Maintenance of ABR and Morphology Following Bullostomy and Transtympanic Injection Procedures
  • 08:28Conclusion

Summary

Automatic Translation

Two microsurgery approaches for local drug delivery to the inner ear are described here and compared in terms of impact on hearing parameters, cochlear cytoarchitecture and expression of inflammatory markers.

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