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En Tissue Displacement-basert Contusive Spinal Cord Injury Model i mus

JoVE Journal
Medicine

This content is Free Access.

JoVE Journal Medicine

A Tissue Displacement-based Contusive Spinal Cord Injury Model in Mice

En Tissue Displacement-basert Contusive Spinal Cord Injury Model i mus

DOI:

10.3791/54988-v

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07:59 min

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June 18, 2017

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Xiangbing Wu*¹, Yi Ping Zhang*², Wenrui Qu, Lisa B. E. Shields, Christopher B. Shields³, Xiao-Ming Xu

¹Spinal Cord and Brain Injury Research Group, Stark Neurosciences Research Institute, Department of Neurological Surgery and Goodman and Campbell Brain and Spine,Indiana University School of Medicine, ²Norton Neuroscience Institute,Norton Healthcare, ³Department of Anatomical Sciences and Neurobiology,University of Louisville

Chapters

00:05Title
01:13Animal Preparation and T10 Spinal Laminectomy
03:06T10 Contusion Injury Using the LISA Impactor
06:13Results: Histologic Assessment of T10 Contusion Injury
07:07Conclusion

Summary

Automatic Translation

Vi introduserer en vevforskyvningsbasert motstridende ryggmargsskademodell som kan produsere en konsekvent kontinær ryggmargsskade hos voksne mus.

Tags

Contusive Spinal Cord Injury Mouse Model C57BL6J Mice Ketamine Xylazine Buprenorphine Carprofen Betadine Alcohol Wipes Ophthalmic Ointment Skin Incision Paraspinal Muscles Agricola Retractor T10 Vertebra Rongeur Dura Mater Impactor

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