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An Ultrasonic Tool for Nerve Conduction Block in Diabetic Rat Models
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Bioengineering
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JoVE Journal Bioengineering
An Ultrasonic Tool for Nerve Conduction Block in Diabetic Rat Models

An Ultrasonic Tool for Nerve Conduction Block in Diabetic Rat Models

DOI:
10.3791/55675-v

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10:27 min

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October 20, 2017

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, , ,
1Institute of Biomedical Engineering and Nanomedicine,National Health Research Institutes, 2Department of Neurology,National Cheng Kung University Hospital

Chapters

  • 00:05Title
  • 00:59Induction and Confirmation of Diabetic Model in Male Adult Sprague-Dawley Rats
  • 01:55Evaluation of Peripheral Diabetic Neuropathy in Diabetic Rats
  • 02:32In Vivo Nerve Conduction Blockage with the HIFU Transducer
  • 08:07Results: Nerve Conduction Block in Diabetic Rats by Ultrasound
  • 09:14Conclusion

Summary

Automatic Translation

Automatic Translation

This work presents the methodology of applying high intensity-focused ultrasound to block the action potentials of diabetic neuropathic nerves.

Tags

Keywords: Ultrasonic ToolNerve Conduction BlockDiabetic Rat ModelsUltrasound Thermal EffectAnalgesiaDiabetic Peripheral NeuropathySTZ-induced DiabetesVon Frey ProbeSciatic Nerve Exposure

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