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Minimally Invasive Muscle Embedding (MIME) – A Novel Experimental Technique to Facilitate Donor-Cell-Mediated Myogenesis
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal Medicine
Minimally Invasive Muscle Embedding (MIME) – A Novel Experimental Technique to Facilitate Donor-Cell-Mediated Myogenesis
DOI:

09:17 min

August 24, 2017

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Chapters

  • 00:05Title
  • 01:25Donor Muscle Tissue Preparation
  • 02:47Minimally Invasive Muscle Embedding (MIME)
  • 04:43Intramuscular Myotoxin Injection to Induce Concerted Muscle Degeneration and Regeneration
  • 05:36Tissue Collection
  • 06:33Evidence of Myogenesis After MIME and Myotoxin Injections
  • 08:01Conclusion

Summary

Automatic Translation

We describe a novel experimental technique that we call Minimally Invasive Muscle Embedding (MIME), which is based on the evidence that skeletal muscle tissue contains viable myogenic cells that can facilitate donor-cell-mediated myogenesis when implanted into a host muscle.

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