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Influenza A Virus undersøgelser i en musemodel af infektion
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Immunology and Infection
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JoVE Journal Immunology and Infection
Influenza A Virus Studies in a Mouse Model of Infection

Influenza A Virus undersøgelser i en musemodel af infektion

DOI:
10.3791/55898-v

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10:44 min

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September 07, 2017

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, ,
1Department of Microbiology and Immunology,University of Rochester School of Medicine and Dentistry

Chapters

  • 00:05Title
  • 01:05Intranasal Infection
  • 01:49Characterization of Viral Pathogenesis
  • 05:29Homogenization of Lungs and Nasal Mucosa and Virus Tritation by Indirect Immunofluorescence
  • 08:30Results: Viral Pathogenesis and Humoral Responses in Influenza A Virus Infected Mice
  • 10:03Conclusion

Summary

Automatic Translation

Automatic Translation

Influenza A virus (IAVs) er vigtige menneskelige respiratorisk patogener. At forstå IAVs patogenicitet og Udfør præklinisk afprøvning af nye vaccine tilgange er dyremodeller efterligne menneskelige fysiologi påkrævet. Her, beskriver vi teknikker til vurdering af IAV patogenese, humorale svar og vaccine virkning ved hjælp af en musemodel af infektion.

Tags

Keywords: Influenza A VirusMouse ModelPathogenesisHumoral ResponseVaccine EfficacyViral InfectionViral PathogenesisImmune ResponseAntiviral TreatmentC57B6 MicePR8 Wild-typeViral DoseLungNasal MucosaEuthanasia

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