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In Vivo EPR vurdering af pH, pO2, Redox Status, og koncentrationen af fosfat og glutathion i Tumor mikromiljø
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
In Vivo EPR Assessment of pH, pO2, Redox Status, and Concentrations of Phosphate and Glutathione in the Tumor Microenvironment
DOI:

10:46 min

March 16, 2018

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Chapters

  • 00:04Title
  • 01:20Probe Synthesis and Calibration
  • 05:42Probe Delivery for In Vivo Functional Measurements
  • 07:18In Vivo Functional Measurements
  • 08:09Results: EPR Assessment in the Tumor Microenvironment
  • 10:04Conclusion

Summary

Automatic Translation

Lav-felt (L-band, 1.2 GHz) elektron paramagnetisk resonans ved hjælp af opløselige nitroxyl og trityl sonder er påvist for vurdering af fysiologisk vigtige parametre i tumor mikromiljø i musemodeller af brystkræft.

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