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Routine Screening Method for Microparticles in Platelet Transfusions
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal Medicine
Routine Screening Method for Microparticles in Platelet Transfusions
DOI:

09:49 min

January 31, 2018

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Chapters

  • 00:05Title
  • 01:02Obtaining a Sample from a Platelet Concentrate
  • 05:04Filling the Sample into the DLS Testing Capillary
  • 06:14Performing the DLS Test
  • 07:21Results: Platelet Activation Status in Platelet Transfusions Measured by Microparticle Content
  • 08:19Conclusion

Summary

Automatic Translation

Platelet inventory management based on screening microparticle content in platelet concentrates is a new quality improvement initiative in hospital blood banks. The goal is to differentiate activated from non-activated platelets to optimize the use of platelets. Providing non-activated platelets to hematology-oncology patients might reduce their high risk to become refractory.

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