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Co transplantation af menneskelige æggestokkene væv med manipuleret endotelceller: en celle-baseret strategi kombinere accelereret Perfusion med direkte Paracrine levering
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Co-transplantation of Human Ovarian Tissue with Engineered Endothelial Cells: A Cell-based Strategy Combining Accelerated Perfusion with Direct Paracrine Delivery
DOI:

07:40 min

May 16, 2018

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Chapters

  • 00:04Title
  • 01:06Encapsulation of Ovarian Tissue
  • 03:40Bilateral Oophorectomy and Co-transplantation of Human Ovarian Tissue with Engineered Endothelial Cells into NSG Mice
  • 05:07Results: Co-transplantation of Human Ovarian Tissue with Endothelial Cells
  • 06:57Conclusion

Summary

Automatic Translation

For nogle patienter er den eneste mulighed for fertilitet bevarelse kryopræservering af æggestokkene væv. Desværre underminerer forsinket revaskularisering follikulært levedygtighed. Vi præsenterer her, en protokol for at co transplant menneskelige æggestokkene væv med endotelceller for udnyttelse som celle-baseret strategi kombinerer accelereret perfusion med en direkte paracrine levering af bioaktive molekyler.

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