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Quantitative Micro-CT Analysis of Aortopathy in a Mouse Model of β-aminopropionitrile-induced Aortic Aneurysm and Dissection
 

Quantitative Micro-CT Analysis of Aortopathy in a Mouse Model of β-aminopropionitrile-induced Aortic Aneurysm and Dissection

Article DOI: 10.3791/57589-v • 06:47 min • July 16th, 2018
July 16th, 2018 •
1, 1, 2, 1, 1, 1,3
1Center for Vascular and Inflammatory Diseases, University of Maryland School of Medicine, 2Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 3Division of Vascular Surgery, University of Maryland School of Medicine

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Summary
Automatic Translation

This article describes a detailed methodology of using a radiopaque lead-based silicone rubber to perfuse the murine vasculature for aortic diameter quantification in a mouse model of aortic aneurysm and dissection.

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Keywords: Micro-CT Analysis Aortopathy Mouse Model β-aminopropionitrile Aortic Aneurysm Aortic Dissection Vascular Biology Vessel Size In Vivo Ex Vivo Quantification Surgical Procedure Anesthesia Isoflurane Intracardiac Perfusion Hemostatic Clamp Heparinized PBS Contrast Agent
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