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Gait Analysis of Age-dependent Motor Impairments in Mice with Neurodegeneration
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Developmental Biology
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JoVE Journal Developmental Biology
Gait Analysis of Age-dependent Motor Impairments in Mice with Neurodegeneration

Gait Analysis of Age-dependent Motor Impairments in Mice with Neurodegeneration

DOI:
10.3791/57752-v

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07:46 min

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June 18, 2018

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,
1European Neuroscience Institute (ENI), 2University Medical Center Göttigen (UMG)

Chapters

  • 00:04Title
  • 00:47Recording of Gait Analysis
  • 02:45Video Processing
  • 06:09Results: Gait Analysis Characterizes Gait and Posture in WT Mice with Advancing Age
  • 06:57Conclusion

Summary

Automatic Translation

Automatic Translation

In this study, we demonstrate the use of kinematic gait analysis based on ventral plane imaging to monitor the subtle changes in motor coordination as well as the progression of neurodegeneration with advancing age in mouse models (e.g., endophilin mutant mouse lines).

Tags

Gait AnalysisMotor ImpairmentsNeurodegenerative DiseasesMouse ModelsParkinson’s DiseaseAtaxiaVideo AnalysisTreadmillPaw PrintGait DynamicsPosture Parameters

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