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Syntesen av 68Ga Core-dopade järnoxid nanopartiklar för dubbla positronemissionstomografi / (T1) Magnetic Resonance Imaging
JoVE Journal
Biology
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JoVE Journal Biology
Synthesis of 68Ga Core-doped Iron Oxide Nanoparticles for Dual Positron Emission Tomography /(T1)Magnetic Resonance Imaging
DOI:

07:26 min

November 20, 2018

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Chapters

  • 00:04Title
  • 00:26Synthesis of Citrate-Coated Iron Oxide Nanoparticles
  • 01:41Synthesis of 68Ga Core-Doped Iron Oxide Nanoparticles (68Ga-C-IONP)
  • 03:19Analysis of 68Ga Core-Doped Iron Oxide Nanoparticles (68Ga-C-IONP)
  • 04:42Results: Characterization of 68Ga Core-Doped Iron Oxide Nanoparticles
  • 06:40Conclusion

Summary

Automatic Translation

Här presenterar vi ett protokoll att erhålla68Ga core-dopade järnoxid nanopartiklar via snabbt mikrovågsugn-driven syntes. Metoden gör PET / (T1) MRI nanopartiklar med radiolabeling effektivitet högre än 90% och radiokemisk renhet av 99% i en 20-minuters syntes.

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