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Behavior
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小鼠 mptp 诱导的帕金森病模型中自发性运动的行为评估
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Behavioral Assessments of Spontaneous Locomotion in a Murine MPTP-induced Parkinson’s Disease Model
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小鼠 mptp 诱导的帕金森病模型中自发性运动的行为评估
DOI:
10.3791/58653-v
•
05:38 min
•
January 07, 2019
•
Pei-En Jiang
,
Qiu-Han Lang
,
Qin-Yi Yu
,
Xin-Yu Tang
,
Qian-Qian Liu
,
Xin-Yu Li
,
Xi-Zeng Feng
1
State Key Laboratory of Medicinal Chemical Biology, The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Science
,
Nankai University
Chapters
00:04
Title
00:42
Cylinder Test
02:44
Open Field Test
03:36
Results: Performance on the Cylinder and Open Field Tests Following MPTP Administration
04:49
Conclusion
Summary
Automatic Translation
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Automatic Translation
我们描述了使用 mptp 建立帕金森病小鼠模型, 以及使用圆筒和开放场测试测量运动功能的行为评估。然后, 我们使用 l-dopa 作为一个例子, 说明如何将这个模型应用于 pd 药物的研究。
Tags
Keywords: Behavioral Assessment
Spontaneous Locomotion
MPTP-induced
Parkinson’s Disease Model
Cylinder Test
Open Field Test
Paw Lift
Motor Function
L-DOPA
Video Recording
Environmental Interference
Acclimation
Sanitization
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