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用于同时测量疼痛和瘙痒相关行为的切面注射模型

JoVE Journal
Neuroscience

This content is Free Access.

JoVE Journal Neuroscience

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors

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用于同时测量疼痛和瘙痒相关行为的切面注射模型

DOI:

10.3791/58943-v

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04:59 min

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September 27, 2019

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Yu Yamanoi^2,3,4, Hiroki Kittaka^2,5, Makoto Tominaga^2,3,6

¹Thermal Biology Group,Exploratory Research Center on Life and Living Systems (ExCELLS), ²Division of Cell Signaling,National Institute for Physiological Sciences, ³Department of Physiological Sciences,Graduate University for Advanced Studies (SOKENDAI), ⁴Research Laboratory,Ikedamohando Co., Ltd., ⁵Department of Molecular Biomedical Sciences, College of Veterinary Medicine,North Carolina State University, ⁶Institute for Environmental and Gender-Specific Medicine,Juntendo University

Chapters

00:04Title
00:53Cheek Injection Model
02:36Neck Injection Model
03:12Results: Representative Pain and Itch-Related Behavior Analyses
04:08Conclusion

Summary

Automatic Translation

通常，小鼠颈部注射模型用于评估尿原引起的划伤行为。然而，该模型只提供有关瘙痒的信息，而不是疼痛的信息。在这里，在小鼠中引入了脸颊注射模型，可用于同时测量疼痛和瘙痒相关行为。

Tags

Keywords: Cheek Injection Model Pain Itch Behavioral Measurement Scratching Wiping Grooming Intradermal Injection Video Recording Mice

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