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Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
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JoVE Journal Neuroscience
Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

DOI:
10.3791/59310-v

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07:03 min

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July 31, 2019

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, , ,
1School of Life Sciences,Guangzhou University, 2Institute for Brain Research and Rehabilitation,South China Normal University, 3School of Life Sciences,South China Normal University

Chapters

  • 00:04Title
  • 00:56Animal Surgery
  • 02:18LFP Recordings in Bilateral M2 of Mice
  • 03:07Cross-correlation Analysis
  • 04:03Coherence Analysis
  • 04:55Results: Cross-correlation and Coherence of Gamma Oscillations between Left and Right M2 of WT and APP/PS1 Mice
  • 06:18Conclusion

Summary

Automatic Translation

Automatic Translation

We present in vivo electrophysiological recording of the local field potential (LFP) in bilateral secondary motor cortex (M2) of mice, which can be applied to evaluate hemisphere lateralization. The study revealed altered levels of synchronization between the left and right M2 in APP/PS1 mice compared to WT controls.

Tags

Keywords: Hemisphere LateralizationBilateral Local Field PotentialSecondary Motor CortexMiceElectrophysiologyNeuronal ActivitySynchronizationAlzheimer’s DiseaseAnesthesiaStereotaxic ApparatusMicroelectrodesM2 RegionLFP RecordingCross-correlation Analysis

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