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Direkte Intrabronchial administration til at forbedre den selektive agens deposition i mus lunge
JoVE Journal
Medicine
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JoVE Journal Medicine
Direct Intrabronchial Administration to Improve the Selective Agent Deposition Within the Mouse Lung
DOI:

07:10 min

May 20, 2019

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Chapters

  • 00:04Title
  • 01:09Non-Operative Intratracheal (IT) Intubation
  • 02:16Intrabronchial (IB) Approach to Distal Right Lung Selective Lobar Cannulation
  • 03:00IB Approach to Distal Left Lung Selective Segmental Cannulation
  • 03:44Right Entire Lung Administration
  • 04:37Left Entire Lung Administration
  • 05:31Results: Representative Effects of Direct IB Selective Agent Administration to Whole Mouse Lung
  • 06:49Conclusion

Summary

Automatic Translation

Intratracheal (IT) administration af eksperimentelle agenter i mus resulterer ofte i asymmetrisk levering til de distale lunger.  I denne rapport beskriver vi en direkte intrabronchial (IB) tilgang til at cannulere hver lunge i levende mus ikke-operativt.  Denne fremgangsmåde kan bruges til selektivt at administrere agenter til en lunge eller kan tilpasses til at forbedre den symmetriske middel levering til begge lunger.

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