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Modificeret Heterotopic Bagekstremitet Osteomyokutane flap model i rotte for Translationel vascularized komposit Allotransplantation forskning
JoVE Journal
Medicine
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JoVE Journal Medicine
Modified Heterotopic Hindlimb Osteomyocutaneous Flap Model in the Rat for Translational Vascularized Composite Allotransplantation Research
DOI:

09:36 min

April 26, 2019

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Chapters

  • 00:04Title
  • 01:05Procedure Overview
  • 02:03Donor Allograft Harvest
  • 05:16Recipient Transplantation Surgery
  • 07:26Results: Histopathological Follow-up and Analysis After Vascularized Composite Allotransplantation (VCA)
  • 09:05Conclusion

Summary

Automatic Translation

Vascularized komposit allograft tilbyder livs ændrelige fordele for transplantations modtagere, men de biologiske årsager til transplantat afvisning og vaskulopati er stadig dårligt forstået. Den gnaver kirurgiske model præsenteret her tilbyder en reproducerbar, klinisk relevant model for transplantation, så forskerne til at vurdere afvisning begivenheder og potentielle terapeutiske strategier for at forhindre deres forekomst.

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