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Murine Model of Metastatic Liver Tumors in the Setting of Ischemia Reperfusion Injury
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Chapters
- 00:04Title
- 00:50Tumor Cell Injection
- 02:37Ischemia and Reperfusion Injury
- 04:27Splenectomy
- 05:06Results: Representative Micrometastasis Evaluation After Murine Tumor Cell Injection
- 05:28Conclusion
We describe in detail a clinically relevant colorectal cancer liver metastases (CRLM) tumor model and the influence of liver ischemia reperfusion (I/R) in tumor growth and metastasis. This model can help to better understand the mechanisms underlying surgery-induced promotion of liver metastatic growth.
