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Generation of a Liver Orthotopic Human Uveal Melanoma Xenograft Platform in Immunodeficient Mice
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JoVE Journal Cancer Research
Generation of a Liver Orthotopic Human Uveal Melanoma Xenograft Platform in Immunodeficient Mice

Generation of a Liver Orthotopic Human Uveal Melanoma Xenograft Platform in Immunodeficient Mice

DOI:
10.3791/59941-v

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04:02 min

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November 06, 2019

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, ,
1Department of Diagnostic and Interventional Radiology,Osaka City University Graduate School of Medicine, 2Department of Surgery, National Hospital Organization,Kure Medical Cancer Center, 3Department of Medical Oncology, Sidney Kimmel Cancer Center,Thomas Jefferson University

Chapters

  • 00:05Title
  • 00:38Patient-Derived Tumor Tissue Surgical Liver Implantation
  • 03:05Results: Representative Computed Tomography Images of Liver Tumors in the Left Lobe of the Liver
  • 03:28Conclusion

Summary

Automatic Translation

Automatic Translation

Orthotopic human liver metastatic uveal melanoma xenograft mouse models were created using surgical orthotopic implantation techniques with patient-derived tumor chunk and needle injection techniques with cultured human uveal melanoma cell lines.

Tags

Keywords: Liver Orthotopic XenograftPatient-derived Tumor Animal ModelUveal MelanomaImmunodeficient MiceTumor ImplantationLiver IncisionAbsorbable HemostatAbsorbable SutureTumor Engraftment

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