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Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
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1Division of Fixed Prosthodontics and Biomaterials, Biomaterials Laboratory,University of Geneva, University Clinic of Dental Medicine, 2Department of Surgery, Division of Oral and Maxillofacial Surgery (HUG), Unity of Oral Surgery and Implantology,University of Geneva, University Clinic of Dental Medicine, 3Department of Surgery, Division of Oral and Maxillofacial surgery (HUG), Laboratory of Oral & Maxillofacial Pathology,University of Geneva, University Clinic of Dental Medicine, 4Division of Fixed Prosthodontics and Biomaterials,University of Geneva, University Clinic of Dental Medicine
Chapters
- 00:04Title
- 01:31Surgery: Anesthesia and Intubation
- 02:46Surgery: Surgical Site Preparation
- 03:18Surgery: Surgical Site Opening
- 04:01Surgery: Cylinder Placement
- 05:01Surgery: Bone Drilling within Area Circumscribed By the Cylinders
- 05:49Surgical Site Closure and Post Surgical Care
- 06:38Results: Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
- 07:35Conclusion
Here we present a surgical protocol in rabbits with the aim to assess bone substitution materials in terms of bone regeneration capacities. By using PEEK cylinders fixed onto rabbit skulls, osteoconduction, osteoinduction, osteogenesis and vasculogenesis induced by the materials may be evaluated either on live or euthanized animals.
