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Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Stochastic Noise Application for the Assessment of Medial Vestibular Nucleus Neuron Sensitivity In Vitro
DOI:

00:06 min

August 28, 2019

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Chapters

  • 00:04Title
  • 00:45Brainstem Preparation
  • 02:27Whole-Cell Patch Clamp Electrophysiology
  • 04:10Sinusoidal and Stochastic Noise Application
  • 04:59Results: Representative Effects of Sinusoidal and Stochastic Noise on MVN Neuronal Firing Rates and Gains
  • 05:57Conclusion

Summary

Automatic Translation

Galvanic vestibular stimulation in humans exhibits improvements in vestibular function. However, it is unknown how these effects occur. Here, we describe how to apply sinusoidal and stochastic electrical noise and evaluate appropriate stimulus amplitudes in individual medial vestibular nucleus neurons in the C57BL/6 mouse.

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