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1Sheikh Zayed Institute for Pediatric Surgical Innovation,Children’s National Hospital, 2Children’s National Heart Institute,Children’s National Hospital, 3Center for Neuroscience Research,Children’s National Hospital, 4Department of Biomedical Engineering, School of Engineering,University of Alabama at Birmingham, 5Department of Pediatrics, Department of Pharmacology & Physiology, School of Medicine and Health Sciences,George Washington University
Chapters
- 00:05Title
- 01:02Heart Excision and Langendorff Perfusion
- 02:42Electrophysiology Study
- 05:17Transmembrane Voltage and Intracellular Calcium Optical Mapping
- 06:55Cleanup
- 07:20Results: Representative Optical Data from Langendorff-Perfused Model Hearts
- 08:59Conclusion
El objetivo de este estudio fue establecer un método para investigar la dinámica cardíaca utilizando un modelo animal traslacional. El enfoque experimental descrito incorpora optocardiografía de doble emisión junto con un estudio electrofisiológico para evaluar la actividad eléctrica en un modelo de corazón porcino aislado e intacto.
