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1Sheikh Zayed Institute for Pediatric Surgical Innovation,Children’s National Hospital, 2Children’s National Heart Institute,Children’s National Hospital, 3Center for Neuroscience Research,Children’s National Hospital, 4Department of Biomedical Engineering, School of Engineering,University of Alabama at Birmingham, 5Department of Pediatrics, Department of Pharmacology & Physiology, School of Medicine and Health Sciences,George Washington University
Chapters
- 00:05Title
- 01:02Heart Excision and Langendorff Perfusion
- 02:42Electrophysiology Study
- 05:17Transmembrane Voltage and Intracellular Calcium Optical Mapping
- 06:55Cleanup
- 07:20Results: Representative Optical Data from Langendorff-Perfused Model Hearts
- 08:59Conclusion
Syftet med denna studie var att etablera en metod för att undersöka hjärtats dynamik med hjälp av en translationell djurmodell. Den beskrivna experimentella metoden innehåller Dual-emission optokardiografi i samband med en Elektrofysiologisk studie för att bedöma elektrisk aktivitet i en isolerad, intakt svin hjärt modell.
