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Dobbelt direkte injektion af blod i Cisterna Magna som en model af Subarachnoid Blødning
JoVE Journal
Neuroscience
Author Produced
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JoVE Journal Neuroscience
Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
DOI:

10:34 min

August 30, 2020

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Chapters

  • 00:00Introduction
  • 02:07Procedure: Setup of SAH Surgery
  • 02:47Procedure: Collection of Blood from a Homologous Mouse Donor
  • 03:25Procedure: Animal Preparation
  • 04:21Procedure: SAH Induction
  • 06:18Post-surgery Procedure
  • 06:42Second Day of Surgery
  • 07:38Representative Results
  • 09:51Conclusion

Summary

Automatic Translation

Vi beskrev i denne protokol en standardiseret subaraknoid blødning (SAH) mus model ved en dobbelt injektion af autologt fuldblod i cisterna magna. Den høje grad af standardisering af dobbelt-injektion procedure repræsenterer en midt-til-akut model af SAH med relativ sikkerhed med hensyn til dødelighed.

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