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Organ Iskæmi-Reperfusion Skade ved at simulere hæmodynamiske ændringer i rottelevertransplantation Model
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JoVE Journal Medicine
Organ Ischemia-Reperfusion Injury by Simulating Hemodynamic Changes in Rat Liver Transplant Model

Organ Iskæmi-Reperfusion Skade ved at simulere hæmodynamiske ændringer i rottelevertransplantation Model

DOI:
10.3791/61779-v

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10:07 min

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March 06, 2021

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, , , , , , , , ,
1Department of Intensive Care Unit,The Second Affiliated Hospital of Guangxi Medical University, 2Department of hepatobiliary surgery,The Affiliated Ningbo Medical Center Lihuili Hospital of Medical School of Ningbo University, 3Department of transplantation,The Second Affiliated Hospital of Guangxi Medical University, 4Digital Technology and Engineering college,Ningbo University of Finance & Economics

Chapters

  • 00:00Introduction
  • 01:35Protocol
  • 02:50Operation
  • 05:41Representative Results: Rats’ Tolerance to Liver Ischemia
  • 06:43Effects of Vascular Ligation on Circulation in Rats
  • 07:09Effects of Hemodynamic Changes on Extrahepatic Organs
  • 09:06Effects of Hemodynamic Changes on Liver, Kidney, Pancreas, Heart Serological Indexes
  • 09:35Conclusion

Summary

Automatic Translation

Automatic Translation

Dette papir giver en detaljeret beskrivelse af, hvordan man opbygger en dyremodel af den anheptiske fase (leveriskæmi) hos rotter for at lette grundforskning i iskæmi-reperfusionsskade efter levertransplantation.

Tags

Organ Ischemia-reperfusion InjuryRat Liver Transplant ModelHemodynamic ChangesAnhepatic PhaseExtrahepatic Organ InvolvementIschemia-reperfusion InjuryLiver TransplantationAnimal ModelAnesthesiaAbdominal SurgeryLiver MobilizationPorta HepatisBile DuctPortal VeinHepatic ArteryAnimal Experiments

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