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Modeling Brain Metastasis Via Tail-Vein Injection of Inflammatory Breast Cancer Cells
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JoVE Journal Cancer Research
Modeling Brain Metastasis Via Tail-Vein Injection of Inflammatory Breast Cancer Cells

Modeling Brain Metastasis Via Tail-Vein Injection of Inflammatory Breast Cancer Cells

DOI:
10.3791/62249-v

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05:02 min

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February 04, 2021

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, , ,
1Department of Breast Medical Oncology,The University of Texas MD Anderson Cancer Center, 2Morgan Welch Inflammatory Breast Cancer Clinic and Research Program,The University of Texas MD Anderson Cancer Center, 3Department of Radiation Oncology,The University of Texas MD Anderson Cancer Center

Chapters

  • 00:04Introduction
  • 00:57Green Fluorescent Protein (GFP) Imaging
  • 02:39GFP Imaging Analysis
  • 03:41Results: Brain Metastasis Visualization and Characterization
  • 04:18Conclusion

Summary

Automatic Translation

Automatic Translation

We describe a xenograft mouse model of breast cancer brain metastasis generated via tail-vein injection of an endogenously HER2-amplified inflammatory breast cancer cell line.

Tags

Brain MetastasisInflammatory Breast CancerTail Vein InjectionMouse ModelGFP ImagingBrain HarvestingStereo MicroscopyFluorescent ImagingBrain Tumor Quantification

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