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En præklinisk model af anstrengende hedeslag hos mus
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JoVE Journal Medicine
A Preclinical Model of Exertional Heat Stroke in Mice

En præklinisk model af anstrengende hedeslag hos mus

DOI:
10.3791/62738-v

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08:22 min

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July 01, 2021

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, , ,
1Department of Applied Physiology and Kinesiology, College of Health and Human Performance,University of Florida, 2Department of Nutrition and Integrative Physiology, College of Health and Human Sciences,Florida State University

Chapters

  • 00:05Introduction
  • 00:55Surgical Implantation of the Telemetric Temperature Monitoring System
  • 02:35EHS Protocol
  • 06:43Results: Exertional Heat Stroke in Mice
  • 07:42Conclusion

Summary

Automatic Translation

Automatic Translation

Protokollen beskriver udviklingen af en standardiseret, gentagelig, præklinisk model af anstrengende hedeslag (EHS) hos mus fri for negative eksterne stimuli såsom elektrisk stød. Modellen giver en platform for mekanistiske, forebyggende og terapeutiske undersøgelser.

Tags

Preclinical ModelExertional Heat StrokeMiceTelemetrySurgical ImplantationCore Temperature MonitoringEnvironmental ChamberAnesthesiaBuprenorphineAseptic TechniqueRecovery

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