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Large Animal Model for Evaluating the Efficacy of the Gene Therapy in Ischemic Heart
JoVE Journal
Medicine
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JoVE Journal Medicine
Large Animal Model for Evaluating the Efficacy of the Gene Therapy in Ischemic Heart
DOI:

06:07 min

September 02, 2021

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Chapters

  • 00:04Introduction
  • 00:45Transthoracic Echocardiography
  • 01:22Coronary Angiography and Left Ventricle Cine Imaging Under Rest and Dobutamine Stress
  • 02:39Ischemia Operation
  • 03:22Gene Transfer
  • 04:00Sample Collection
  • 04:41Results: Assessment of Gene Therapy Efficacy
  • 05:26Conclusion

Summary

Automatic Translation

Myocardial gene therapy for ischemic heart disease holds great promise for future therapeutics. Here, we introduce a large animal model for evaluating the efficacy of gene therapy in the ischemic heart.

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