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1Department of Rehabilitation for Motor Functions,National Rehabilitation Center for Persons with Disabilities, 2Department of Assistive Technology,National Rehabilitation Center for Persons with Disabilities, 3Department of Metabolism and Endocrinology, Graduate School of Medicine,Juntendo University, 4Department of Rehabilitation Medicine,Graduate School of Medicine, The University of Tokyo, 5Department of Clinical Research,National Rehabilitation Center for Persons with Disabilities
Chapters
- 00:05Introduction
- 00:35Measurement of Magnitudes of Accelerations and Adjustment of the PHM System
- 01:33Quantification of Mouse Head-Twitch Response
- 02:03Immunohistochemical Analysis of Prefrontal Cortex (PFC) Collected from Euthanized Mouse Brain
- 03:22Results: Effect of Treadmill Running and PHM Application in Mouse PFC Neurons
- 04:37Conclusion
The present protocol describes a custom-designed ''passive head motion'' system, which reproduces mechanical accelerations at rodents' heads generated during their treadmill running at moderate velocities. It allows dissecting mechanical factors/elements from the beneficial effects of physical exercise.
