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Retinal patofysiologisk evaluering i en rottemodel
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JoVE Journal Medicine
Retinal Pathophysiological Evaluation in a Rat Model

Retinal patofysiologisk evaluering i en rottemodel

DOI:
10.3791/63111-v

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09:11 min

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May 06, 2022

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1Translational Pharmaceutics Research Laboratory (TPRL), Department of Pharmacy,Birla Institute of Technology & Science — Pilani, Hyderabad Campus

Chapters

  • 00:09Introduction
  • 01:11Retinal Histology
  • 03:40Blood Retinal Barrier Breakdown Assay
  • 05:15Fluorescence Angiography
  • 07:09Representative Results
  • 08:40Conclusion

Summary

Automatic Translation

Automatic Translation

Diabetisk retinopati er en af de førende årsager til blindhed. Histologi, blod-retinal barriere nedbrydning assay og fluorescens angiografi er værdifulde teknikker til at forstå nethinden patofysiologi, hvilket yderligere kan forbedre den effektive lægemiddelscreening mod diabetisk retinopati.

Tags

Retinal PathophysiologyDiabetic RetinopathyStreptozotocin-induced Diabetic RetinopathyRat ModelHistologyBRB Breakdown AssayFluorescein AngiographyFITC-dextranEnucleationFixationDehydrationParaffin EmbeddingMicrotome

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