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秀 丽隐杆线虫 感染模型中的遗传免疫研究
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Immunology and Infection
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JoVE Journal Immunology and Infection
Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection
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秀 丽隐杆线虫 感染模型中的遗传免疫研究

DOI:
10.3791/63636-v

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09:24 min

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April 06, 2022

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, ,
1Department of Molecular Genetics,University of Toronto

Chapters

  • 00:04Introduction
  • 00:50Infection of C. elegans with N. Parisiito Yield Immune-Primed Offspring
  • 03:30Testing Inherited Immunity to N. Parisii in C. elegans and Analysis of DY96-Stained Worms to Assess Infection Status
  • 06:10Results: Study of Inherited Immunity in Genetically Tractable Worm Model
  • 08:32Conclusion

Summary

Automatic Translation

Automatic Translation

秀丽隐杆线虫感染秀丽隐杆线虫感染使蠕虫能够产生对相同病原体具有高度抗性的后代。这是遗传免疫的一个例子，遗传免疫是一种鲜为人知的表观遗传现象。本方案描述了在遗传可处理的蠕虫模型中遗传免疫的研究。

Tags

Keywords: Caenorhabditis ElegansMicrosporidiaInherited ImmunityIntergenerational ImmunityInfectionSporesWormsOP50M9 MediaNematode Growth MediumCentrifugationMicroscopy

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