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成年绵羊模型中自体心包经导管肺动脉瓣置换术，使用自扩展镍钛诺支架

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JoVE Journal Medicine

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

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成年绵羊模型中自体心包经导管肺动脉瓣置换术，使用自扩展镍钛诺支架

DOI:

10.3791/63661-v

•

05:31 min

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June 08, 2022

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Yimeng Hao², Xiaolin Sun², Jonathan Frederik Sebastian Kiekenap, Jasper Emeis, Marvin Steitz, Alexander Breitenstein-Attach, Felix Berger², Boris Schmitt^2,3,4,5

¹Department of Pediatric Cardiology and Congenital Heart Disease,Charité University Medicine Berlin, ²Department of Pediatric Cardiology and Congenital Heart Disease,Deutsches Herzzentrum Berlin, ³DZHK (German Centre for Cardiovascular Research) and BMBF (German Ministry of Education and Research), ⁴BIH (Berlin Institute of Health), ⁵BCRT (BIH Center of Regenerative Therapies)

Chapters

00:05Introduction
01:12Transcatheter Autologous Pulmonary Valve Implantation via the Left Jugular Vein
03:33Results: Implantation of Autologous Pulmonary Valves in Adult Sheep
04:54Conclusion

Summary

Automatic Translation

本研究证明了通过在成年绵羊模型中使用自膨胀镍钛诺支架来开发自体肺动脉瓣植入原体肺动脉瓣位置的可行性和安全性。这是为右心室流出道功能障碍患者开发经导管肺动脉瓣置换术的一步。

Tags

Autologous Pericardium Self-expandable Nitinol Stent Transcatheter Pulmonary Valve Replacement TPVR Right Ventricular Outflow Tract Cardiac-computed Tomography Intra-cardiac Echocardiography Fluoroscopy Angiography Delivery System Valve Implantation

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