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Intestinal epitelregenerering som reaktion på ioniserende bestråling
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JoVE Journal Biology
Intestinal Epithelial Regeneration in Response to Ionizing Irradiation

Intestinal epitelregenerering som reaktion på ioniserende bestråling

DOI:
10.3791/64028-v

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09:10 min

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July 27, 2022

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, , , ,
1Department of Medicine,Renaissance School of Medicine at Stony Brook University, 2Department of Physiology and Biophysics,Renaissance School of Medicine at Stony Brook University

Chapters

  • 00:04Introduction
  • 01:24Preparation
  • 02:41Total‐Body Gamma Irradiation and Tissue Collection
  • 06:22Results: Analysis of Small Intestine Sections after Irradiation
  • 08:18Conclusion

Summary

Automatic Translation

Automatic Translation

Mave-tarmkanalen er et af de mest følsomme organer for skade ved stråleterapeutiske kræftbehandlinger. Det er samtidig et organsystem med en af de højeste regenerative kapaciteter efter sådanne fornærmelser. Den præsenterede protokol beskriver en effektiv metode til at studere tarmepithelets regenerative kapacitet.

Tags

Keywords: Intestinal Epithelial RegenerationIonizing RadiationGamma IrradiationColorectal CancerLineage TracingTamoxifenEdUBouin’s FixativeGamma IrradiatorCre-mediated Recombination

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