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Measuring Skeletal Muscle Thermogenesis in Mice and Rats
JoVE Journal
Behavior
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JoVE Journal Behavior
Measuring Skeletal Muscle Thermogenesis in Mice and Rats
DOI:

07:56 min

July 27, 2022

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Chapters

  • 00:04Introduction
  • 00:55Program Transponders, Surgery and Postoperative Care
  • 02:54Testing Preparation: Home Cage
  • 03:33Temperature Testing: Home Cage
  • 04:44Temperature Testing: Treadmill Walking
  • 06:08Results: Analysis of Thermogenesis in Response to Contextual and Pharmacological Stimuli
  • 07:30Conclusion

Summary

Automatic Translation

Mice and rats are surgically implanted with remote temperature transponders and then habituated to the testing environment and procedure. Changes in muscle temperature are measured in response to pharmacological or contextual stimuli in the home cage or during prescribed physical activity (i.e., treadmill walking at a constant speed).

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