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1Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College,Huazhong University of Science and Technology, 2Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiological Disorders, Tongji Hospital, Tongji Medical College,Huazhong University of Science and Technology
Chapters
- 00:04Introduction
- 00:33Preparation of Surgical Instruments
- 01:11Animal Preparation
- 02:04Constriction of Transverse Aorta and Postoperative Care
- 03:46Results: Measurement of Heart Function via Ultrasound Imaging System
- 04:15Conclusion
The present protocol describes a modified and simplified technique with a minimally invasive transverse aortic constriction (TAC) procedure using a self-made retractor. This procedure can be conducted without a ventilator or microscope and introduces pressure overload, eventually leading to cardiac hypertrophy or heart failure.
