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Model of Ischemia and Reperfusion Injury in Rabbits
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Model of Ischemia and Reperfusion Injury in Rabbits

Model of Ischemia and Reperfusion Injury in Rabbits

DOI:
10.3791/64752-v

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06:11 min

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November 03, 2023

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, , , ,
1Department of Cardiac Surgery, Boston Children’s Hospital,Harvard Medical School

Chapters

  • 00:00Introduction
  • 00:52Mini‐Thoracotomy (Survival)
  • 02:25LAD Artery Isolation and Incision Closure
  • 03:23Midline Sternotomy (Non‐Survival) and LAD Artery Isolation
  • 04:18Coronary Artery Occlusion and Ischemia Confirmation
  • 04:52Results: Analysis of Acute Regional Myocardial Ischemia in a Rabbit Model
  • 05:29Conclusion

Summary

Automatic Translation

Automatic Translation

The present study demonstrates a highly reproducible animal model of acute regional myocardial ischemia and reperfusion injury in rabbits using a left mini-thoracotomy for survival cases or a midline sternotomy for non-survival cases.

Tags

Rabbit ModelIschemia-reperfusion InjuryLAD ArteryMini-thoracotomySurvival StudyPericardial Sac3-0 Polypropylene SuturePolyglactin 910 StitchesLow Technical Demand

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