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Journal
/
Cancer Research
/
In Vivo Brain Tumor Modeling via Electroporation-Based Delivery of Plasmid DNA
/
使用基于电穿孔的质粒DNA递送对
体内
脑肿瘤进行建模,以代表患者突变特征
JoVE Journal
Cancer Research
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JoVE Journal
Cancer Research
Modeling Brain Tumors
In Vivo
Using Electroporation-Based Delivery of Plasmid DNA Representing Patient Mutation Signatures
Please note that all translations are automatically generated.
Click here for the English version.
使用基于电穿孔的质粒DNA递送对
体内
脑肿瘤进行建模,以代表患者突变特征
In Vivo Brain Tumor Modeling via Electroporation-Based Delivery of Plasmid DNA
DOI:
10.3791/65286-v
•
02:03 min
•
June 23, 2023
•
Katie B. Grausam*
1
,
Joshua J. Breunig*
1,2,3,4,5
1
Board of Governor’s Regenerative Medicine Institute
,
Cedars-Sinai Medical Center
,
2
Center for Neural Sciences in Medicine
,
Cedars-Sinai Medical Center
,
3
Department of Biomedical Sciences
,
Cedars-Sinai Medical Center
,
4
Samuel Oschin Comprehensive Cancer Institute
,
Cedars-Sinai Medical Center
,
5
Department of Medicine, David Geffen School of Medicine
,
University of California, Los Angeles
Tags
Keywords: Glioblastoma
Brain Tumor
In Vivo Modeling
Electroporation
Plasmid DNA
Patient Mutation Signatures
Immunocompetent Mouse Model
Tumor Microenvironment
Immunotherapy
Autochthonous Tumor Growth
Preclinical Trials
DNA Plasmids
Neural Precursor Cells
MADR Method
Somatic Mutagenesis
Driver Mutations
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check_url/65286?article_type=v
使用基于电穿孔的质粒DNA递送对
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check_url/65286?article_type=v
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