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Journal
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Biochemistry
/
Measuring Ubiquitylated, SUMOylated, and ADP-Ribosylated DNA-Protein Crosslinks
/
Detecção quantitativa de ligações cruzadas DNA-proteína e suas modificações pós-traducionais
JoVE Journal
Biochemistry
This content is Free Access.
JoVE Journal
Biochemistry
Quantitative Detection of DNA-Protein Crosslinks and Their Post-Translational Modifications
Detecção quantitativa de ligações cruzadas DNA-proteína e suas modificações pós-traducionais
Measuring Ubiquitylated, SUMOylated, and ADP-Ribosylated DNA-Protein Crosslinks
DOI:
10.3791/65315-v
•
03:20 min
•
April 21, 2023
•
Yilun Sun
1
Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute
,
National Institutes of Health
Tags
Keywords: DNA-protein Crosslinks
DNA Damage Repair
Topoisomerase Inhibitors
PARP Inhibitors
Aldehydes
Post-translational Modifications
Deubiquitylation
SUMOylation
ADP-ribosylation
In Vivo Complex Of Enzyme Assay
Rapid Approach To DNA Adduct Recovery Assay
Immunofluorescence
Quantitation
Kinetics
Formation
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