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Harnessing iPSC-Derived iTenocytes for Effective Cell-Based Therapy

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通过联合巩膜过表达和 2D 单轴张力产生诱导多能干细胞衍生的 iTenocytes

JoVE Journal
Bioengineering

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JoVE Journal Bioengineering

Generation of Induced Pluripotent Stem Cell-Derived iTenocytes via Combined Scleraxis Overexpression and 2D Uniaxial Tension

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通过联合巩膜过表达和 2D 单轴张力产生诱导多能干细胞衍生的 iTenocytes

Harnessing iPSC-Derived iTenocytes for Effective Cell-Based Therapy

DOI:

10.3791/65837-v

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01:43 min

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March 01, 2024

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Victoria Yu^2,3, Angela Papalamprou^2,3, Dmitriy Sheyn^2,3,4,5

¹Orthopaedic Stem Cell Research Laboratory,Cedars-Sinai Medical Center, ²Board of Governors Regenerative Medicine Institute,Cedars-Sinai Medical Center, ³Department of Biomedical Sciences,Cedars-Sinai Medical Center, ⁴Department of Orthopedics,Cedars-Sinai Medical Center, ⁵Department of Surgery,Cedars-Sinai Medical Center

Tags

Induced Pluripotent Stem Cells ITenocytes Scleraxis Uniaxial Tension Tendon Injury Mesenchymal Stromal Cells Tendon Differentiation Tendon Regeneration Mechanoregulation Biomaterials

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