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Journal
/
Bioengineering
/
Streamlined Protocol for Mouse CAR-T Cell Generation in Syngeneic Models
/
Geração Eficiente de Células T do Receptor de Antígeno Quimérico Murino (CAR)-T
JoVE Journal
Bioengineering
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JoVE Journal
Bioengineering
Efficient Generation of Murine Chimeric Antigen Receptor (CAR)-T Cells
Geração Eficiente de Células T do Receptor de Antígeno Quimérico Murino (CAR)-T
Streamlined Protocol for Mouse CAR-T Cell Generation in Syngeneic Models
DOI:
10.3791/65887-v
•
00:52 min
•
February 02, 2024
•
Rosa L. Vincent
,
Fangda Li
,
Edward R. Ballister
,
Nicholas Arpaia
3
,
Tal Danino
3,4
1
Department of Biomedical Engineering
,
Columbia University
,
2
Department of Microbiology & Immunology, Vagelos College of Physicians and Surgeons
,
Columbia University
,
3
Herbert Irving Comprehensive Cancer Center
,
Columbia University
,
4
Data Science Institute
,
Columbia University
Tags
Keywords: Murine CAR-T Cells
Chimeric Antigen Receptor T-cells
Syngeneic Tumor Models
Retroviral Transduction
Ex Vivo T Cell Culture
Solid Tumor Treatment
Immune System
Tumor Microenvironment (TME)
Engineered Cell Therapies
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Geração Eficiente de Células T do Receptor de Antígeno Quimérico Murino (CAR)-T
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