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Journal
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Neuroscience
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A 3D Blood-Brain Barrier Model Derived from Human Pluripotent Stem-Cells
/
신경 질환을 모델링하고 치료적으로 표적화하기 위한
체외
혈액-뇌 장벽 재건
JoVE Journal
Neuroscience
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JoVE Journal
Neuroscience
Reconstruction of the Blood-Brain Barrier
In Vitro
to Model and Therapeutically Target Neurological Disease
Please note that all translations are automatically generated.
Click here for the English version.
신경 질환을 모델링하고 치료적으로 표적화하기 위한
체외
혈액-뇌 장벽 재건
A 3D Blood-Brain Barrier Model Derived from Human Pluripotent Stem-Cells
DOI:
10.3791/65921-v
•
02:09 min
•
October 20, 2023
•
Camille Goldman*
1,2,3,4,5
,
Natalie Suhy*
1,2,3,4,5
,
Jessica E. Schwarz
2,3,4,5
,
Emily Ruth Sartori
2,3,4,5
,
Rikki B. Rooklin
2,3,4,5
,
Braxton R. Schuldt
2,3,4,5
,
Louise A. Mesentier-Louro
2,3,4,5
,
Joel W. Blanchard
2,3,4,5
1
Icahn School of Medicine at Mount Sinai
,
2
Black Family Stem Cell Institute at Mount Sinai
,
3
Ronald M. Loeb Center for Alzheimer’s Disease at Mount Sinai
,
4
Friedman Brain Institute at Mount Sinai
,
5
Nash Family Department of Neuroscience at Mount Sinai
Tags
Blood-brain Barrier
In Vitro Model
Alzheimer’s Disease
Neurodegeneration
Cerebrovascular Pathology
APOE4
Amyloid
Induced Pluripotent Stem Cells
Personalized Therapy
Drug Screening
3D Model
BBB Function
Cerebral Amyloid Angiopathy
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