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Journal
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Neuroscience
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A 3D Blood-Brain Barrier Model Derived from Human Pluripotent Stem-Cells
/
Rekonstruksjon av blod-hjernebarrieren
in vitro
for å modellere og terapeutisk målrette nevrologisk sykdom
JoVE Journal
Neuroscience
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JoVE Journal
Neuroscience
Reconstruction of the Blood-Brain Barrier
In Vitro
to Model and Therapeutically Target Neurological Disease
Rekonstruksjon av blod-hjernebarrieren
in vitro
for å modellere og terapeutisk målrette nevrologisk sykdom
A 3D Blood-Brain Barrier Model Derived from Human Pluripotent Stem-Cells
DOI:
10.3791/65921-v
•
02:09 min
•
October 20, 2023
•
Camille Goldman*
1,2,3,4,5
,
Natalie Suhy*
1,2,3,4,5
,
Jessica E. Schwarz
2,3,4,5
,
Emily Ruth Sartori
2,3,4,5
,
Rikki B. Rooklin
2,3,4,5
,
Braxton R. Schuldt
2,3,4,5
,
Louise A. Mesentier-Louro
2,3,4,5
,
Joel W. Blanchard
2,3,4,5
1
Icahn School of Medicine at Mount Sinai
,
2
Black Family Stem Cell Institute at Mount Sinai
,
3
Ronald M. Loeb Center for Alzheimer’s Disease at Mount Sinai
,
4
Friedman Brain Institute at Mount Sinai
,
5
Nash Family Department of Neuroscience at Mount Sinai
Tags
Blood-brain Barrier
In Vitro Model
Alzheimer’s Disease
Neurodegeneration
Cerebrovascular Pathology
APOE4
Amyloid
Induced Pluripotent Stem Cells
Personalized Therapy
Drug Screening
3D Model
BBB Function
Cerebral Amyloid Angiopathy
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