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Journal
/
Biology
/
A Physiologically-Relevant All-Human 2D+ Hepatic System for Drug Discovery
/
Um Sistema de Cultura Hepática Totalmente Humano para Aplicações no Desenvolvimento de Fármacos
JoVE Journal
Biology
This content is Free Access.
JoVE Journal
Biology
An All-Human Hepatic Culture System for Drug Development Applications
Um Sistema de Cultura Hepática Totalmente Humano para Aplicações no Desenvolvimento de Fármacos
A Physiologically-Relevant All-Human 2D+ Hepatic System for Drug Discovery
DOI:
10.3791/65992-v
•
01:11 min
•
October 20, 2023
•
Justin J. Odanga
,
Elena Gianulis
,
Lindsey Whaley
,
Edward L. LeCluyse
,
Sharon Presnell
,
Jessica R. Weaver
1
Institute of Regenerative Medicine
,
LifeNet Health
,
2
Biologics Division
,
LifeNet Health
,
3
LifeSciences Division
,
LifeNet Health
,
4
Research and Development
,
LifeSciences, LifeNet Health
Tags
Hepatic Culture System
Primary Human Hepatocytes
In Vitro Platform
Drug Development
Pharmacokinetics
Metabolic Clearance
Phenotypic Stability
Reproducibility
TruVivo
2D+ Culture
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