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Three-Step Organoid Model for Tendon Research and Engineering

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Demonstration af selvsamlet cellearkkultur og manuel generering af en 3D-sene-/ledbåndslignende organoid ved hjælp af humane dermale fibroblaster

JoVE Journal
Bioengineering
Author Produced

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JoVE Journal Bioengineering

Demonstration of Self-Assembled Cell Sheet Culture and Manual Generation of a 3D Tendon/Ligament-Like Organoid by using Human Dermal Fibroblasts

Demonstration af selvsamlet cellearkkultur og manuel generering af en 3D-sene-/ledbåndslignende organoid ved hjælp af humane dermale fibroblaster

Three-Step Organoid Model for Tendon Research and Engineering

DOI:

10.3791/66047-v

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00:54 min

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June 21, 2024

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Ana Luísa Graça, Niklas Kroner-Weigl, Viviana Reyes Alcaraz, Sigrid Müller-Deubert, Maximilian Rudert, Denitsa Docheva

¹Department of Musculoskeletal Tissue Regeneration, Orthopaedic Hospital König-Ludwig-Haus,University of Würzburg, ²Laboratory for Experimental Trauma Surgery, Department of Trauma Surgery,University Hospital Regensburg, ³Department of Orthopaedics, Orthopaedic Hospital König-Ludwig-Haus,University of Würzburg

Tags

3D Organoid Tendon/ligament Fibroblasts Self-assembled Cell Sheet Regenerative Medicine Extracellular Matrix In Vitro Tenogenesis Dynamic Mechanical Stimulation Cell Differentiation

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