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Journal
/
Biochemistry
/
Development of a Click-Based Assay for Screening HAT1 Enzyme Activity
/
Histon Asetiltransferaz 1 Asetilasyonunu Ölçmek için Bir Asetil-Tıklama Kimyası Testi
JoVE Journal
Biochemistry
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JoVE Journal
Biochemistry
An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation
Please note that all translations are automatically generated.
Click here for the English version.
Histon Asetiltransferaz 1 Asetilasyonunu Ölçmek için Bir Asetil-Tıklama Kimyası Testi
Development of a Click-Based Assay for Screening HAT1 Enzyme Activity
DOI:
10.3791/66054-v
•
01:28 min
•
January 26, 2024
•
Shreenidhi Rajkumar
,
Danielle Dixon
,
Andrew M. Lipchik
,
Joshua J. Gruber
1
Departments of Internal Medicine and the Green Center for Reproductive Biology Sciences
,
University of Texas Southwestern Medical Center
,
2
Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences
,
Wayne State University
Tags
Keywords: Acetyl-Click Chemistry Assay
Histone Acetyltransferase 1 (HAT1)
Acetyl Transferase Activity
High Throughput Screening
Small Molecule Inhibitors
Peptide Substrate
Enzymatic Assay
Chromatin Synthesis
Tumor Growth
Cancer Treatment
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