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Journal
/
Medicine
/
Investigating HFpEF Pathophysiology in a Hyperlipidemia-Induced Mouse Model
/
射血分数保留的高脂血症诱导心力衰竭小鼠模型
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal
Medicine
A Murine Model of Hyperlipidemia-Induced Heart Failure with Preserved Ejection Fraction
Please note that all translations are automatically generated.
Click here for the English version.
射血分数保留的高脂血症诱导心力衰竭小鼠模型
Investigating HFpEF Pathophysiology in a Hyperlipidemia-Induced Mouse Model
DOI:
10.3791/66442-v
•
01:59 min
•
March 29, 2024
•
Monique Williams
2
,
Ali Kamiar
3
,
Jose Manuel Condor Capcha
2
,
Monica Anne Rasmussen
,
Qusai Alitter
,
Rosemeire Kanashiro Takeuchi
3
,
Lauro Mitsuru Takeuchi
,
Joshua M. Hare
2
,
Lina A. Shehadeh
2
1
Department of Medicine, Division of Cardiology
,
University of Miami Leonard M. Miller School of Medicine
,
2
Interdisciplinary Stem Cell Institute
,
University of Miami Leonard M. Miller School of Medicine
,
3
Department of Molecular and Cellular Pharmacology
,
University of Miami Leonard M. Miller School of Medicine
,
4
Department of Medical Education
,
University of Miami Leonard M. Miller School of Medicine
Tags
Hyperlipidemia
Heart Failure With Preserved Ejection Fraction (HFpEF)
Murine Model
Poloxamer-407 (P-407)
Adeno-associated Virus 9-cardiac Troponin T-low-density Lipoprotein Receptor (AAV9-cTnT-LDLR)
Diastolic Dysfunction
Cardiac Ischemia
Metabolic Syndrome
Lipotoxicity
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