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Journal
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Medicine
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Investigating HFpEF Pathophysiology in a Hyperlipidemia-Induced Mouse Model
/
Modèle murin d’insuffisance cardiaque induite par l’hyperlipidémie avec fraction d’éjection préservée
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal
Medicine
A Murine Model of Hyperlipidemia-Induced Heart Failure with Preserved Ejection Fraction
Please note that all translations are automatically generated.
Click here for the English version.
Modèle murin d’insuffisance cardiaque induite par l’hyperlipidémie avec fraction d’éjection préservée
Investigating HFpEF Pathophysiology in a Hyperlipidemia-Induced Mouse Model
DOI:
10.3791/66442-v
•
01:59 min
•
March 29, 2024
•
Monique Williams
2
,
Ali Kamiar
3
,
Jose Manuel Condor Capcha
2
,
Monica Anne Rasmussen
,
Qusai Alitter
,
Rosemeire Kanashiro Takeuchi
3
,
Lauro Mitsuru Takeuchi
,
Joshua M. Hare
2
,
Lina A. Shehadeh
2
1
Department of Medicine, Division of Cardiology
,
University of Miami Leonard M. Miller School of Medicine
,
2
Interdisciplinary Stem Cell Institute
,
University of Miami Leonard M. Miller School of Medicine
,
3
Department of Molecular and Cellular Pharmacology
,
University of Miami Leonard M. Miller School of Medicine
,
4
Department of Medical Education
,
University of Miami Leonard M. Miller School of Medicine
Tags
Hyperlipidemia
Heart Failure With Preserved Ejection Fraction (HFpEF)
Murine Model
Poloxamer-407 (P-407)
Adeno-associated Virus 9-cardiac Troponin T-low-density Lipoprotein Receptor (AAV9-cTnT-LDLR)
Diastolic Dysfunction
Cardiac Ischemia
Metabolic Syndrome
Lipotoxicity
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