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Sex-Specific Glial Biomarkers in Alzheimer's Disease: A Transcriptome Analysis

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Identifiering av biomarkörer för könsspecificitet av Alzheimers sjukdom baserat på gliatranskriptomprofilerna

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

Biomarker Identification for Gender Specificity of Alzheimer’s Disease Based on the Glial Transcriptome Profiles

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Identifiering av biomarkörer för könsspecificitet av Alzheimers sjukdom baserat på gliatranskriptomprofilerna

Sex-Specific Glial Biomarkers in Alzheimer's Disease: A Transcriptome Analysis

DOI:

10.3791/66552-v

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01:01 min

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May 20, 2024

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Hanjie Liu*¹, Hui Yang*², Shuqing Liu, Siyu Li, Wen Yang, Anwar Ayesha, Xin Tan, Cen Jiang, Yi Liu, Lushuang Xie

¹Chengdu University of Traditional Chinese Medicine, ²Chengdu Shuangliu Hospital of Traditional Chinese Medicine, ³Department of Automation,Tsinghua University, ⁴Affiliated Reproductive & Women-Children Hospital,Chengdu University of Traditional Chinese Medicine, ⁵Department of Neurology, Dalian Municipal Central Hospital,Central Hospital of Dalian University of Technology

Tags

Alzheimer’s Disease Biomarkers Gender Specificity Glial Cells Transcriptome Single-cell RNA Sequencing NLGN4Y Astrocytes Microglia Oligodendrocytes Gene Ontology KEGG Pathway Protein-protein Interaction Gene-transcription Factor-miRNA Network Ecklonia Kurome Okam Herba Ephedrae

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