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A Preclinical Model to Assess Brain Recovery After Acute Stroke in Rats
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Neuroscience
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JoVE Journal Neuroscience
A Preclinical Model to Assess Brain Recovery After Acute Stroke in Rats

A Preclinical Model to Assess Brain Recovery After Acute Stroke in Rats

DOI:
10.3791/60166-v

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10:15 min

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November 06, 2019

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, , , , , , , , ,
1Beijing Yinfeng Dingcheng Biological Engineering Technology Ltd., 2Hulunbuir People’s Hospital, 3Shandong Qilu Stem Cell Engineering Co. Ltd.

Chapters

  • 00:04Title
  • 00:29Establishment of a Unilateral MCAO/R Model in Rats
  • 03:32TTC Staining
  • 06:10Assessment of Sensorimotor Function
  • 07:50Results: Assessment of Brain Recovery after Acute Stroke in Rats
  • 09:37Conclusion

Summary

Automatic Translation

Automatic Translation

The purpose of this study is to establish and validate an animal model for research in the recovery and sequela stages of brain ischemia by testing brain infarction and sensorimotor function after middle cerebral artery occlusion/reperfusion (MCAO/R) after 1-90 days in rats.

Tags

Preclinical ModelBrain RecoveryAcute StrokeRat ModelCerebral IschemiaCommon Carotid ArteryExternal Carotid ArteryInternal Carotid ArteryMiddle Cerebral ArteryThread BoltAnesthesiaSurgical ProcedureAseptic Technique

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