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Electrocardiogram Recordings in Anesthetized Mice using Lead II
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Electrocardiogram Recordings in Anesthetized Mice using Lead II

Electrocardiogram Recordings in Anesthetized Mice using Lead II

DOI:
10.3791/61583-v

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04:16 min

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June 20, 2020

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, ,
1Department of Biochemistry and Molecular Biology, School of Medicine,Kyung Hee University

Chapters

  • 00:00Introduction
  • 00:56ECG Measurement
  • 02:38Results: ECG Measurements in Mice Treated with Agonists and Antagonists of the Autonomic Nervous System
  • 03:25Conclusion

Summary

Automatic Translation

Automatic Translation

We present an ECG protocol that is technically easy, inexpensive, fast, and affordable in small mice, and can be performed with enhanced sensitivity. We suggest this method as a screening approach for studying pharmacological agents, genetic modifications, and disease models in mice.

Tags

Keywords: ElectrocardiogramECGAnesthetized MiceLead IICardiac ConductionArrhythmiaAutonomic Nervous SystemHeart RateQTc IntervalAtropineIsoprenalineCarbacholBALB/c MiceBio AmplifierData AcquisitionAnalysis Software

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